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IL-7 Knocks the Socs Off Chronic Viral Infection

Date

Authors

Parish, Ian

Kaech, Susan

Publisher

Cell Press

Abstract

Chronic viral infections represent a major burden to human health, and modulation of the immune system is emerging as a novel approach to fighting such infections. Pellegrini et al. (2011) demonstrate that treatment with the cytokine IL-7 may reinvigorate the immune response to persistent infection by targeting immunosuppressive Socs3 proteins.

Keywords

Keywords: interleukin 10; interleukin 6; interleukin 7; suppressor of cytokine signaling 3; transforming growth factor beta; acquired immune deficiency syndrome; chronic disease; hepatitis B; hepatitis C; Hepatitis C virus; homeostasis; human; Human immunodeficienc

URI

http://hdl.handle.net/1885/37559

Collections

ANU Research Publications

Source

Cell

Type

Journal article

DOI

10.1016/j.cell.2011.01.038

Restricted until

2037-12-31

Downloads

File

Description

01_Parish_IL-7_Knocks_the_Socs_Off_2011.pdf (104.68 KB)