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Pioglitazone acutely reduces energy metabolism and insulin secretion in rats

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Date

2013

Authors

Lamontagne, Julien
Jalbert-Arsenault, Élise
Pepin, Emilie
Peyot, Marie-Line
Ruderman, Neil
Nolan, Christopher
Joly, Erik
Madiraju, Murthy S R
Poitout, Vincent
Prentki, Marc

Journal Title

Journal ISSN

Volume Title

Publisher

American Diabetes Association

Abstract

Our objective was to determine if the insulin-sensitizing drug pioglitazone acutely reduces insulin secretion and causes metabolic deceleration in vivo independently of change in insulin sensitivity. We assessed glucose homeostasis by hyperinsulinemiceugl

Description

Keywords

Keywords: glucose; insulin; peroxisome proliferator activated receptor gamma; pioglitazone; animal experiment; animal model; article; calorimetry; controlled study; core temperature; energy expenditure; energy metabolism; glucose blood level; hyperglycemia; hyperin

Citation

URI

http://hdl.handle.net/1885/74445

Collections

ANU Research Publications

Source

Diabetes

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.2337/db12-0428

Restricted until

2037-12-31

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Description
01_Lamontagne_Pioglitazone_acutely_reduces_2013.pdf (7.18 MB)

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