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Extent of systemic spread determines CD8+ T cell immunodominance for laboratory strains, smallpox vaccines, and zoonotic isolates of vaccinia virus

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Date

2015

Authors

Flesch, Inge
Hollett (previously Noel), Natasha
Wong, Yik Chun
Quinan, Barbara
Howard, Debbie
da Fonseca, Flavio G.
Tscharke, David

Journal Title

Journal ISSN

Volume Title

Publisher

American Association of Immunologists

Abstract

CD8+ T cells that recognize virus-derived peptides presented on MHC class I are vital antiviral effectors. Such peptides presented by any given virus vary greatly in immunogenicity, allowing them to be ranked in an immunodominance hierarchy. However, the

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Keywords

Citation

URI

http://hdl.handle.net/1885/76906

Collections

ANU Research Publications

Source

Journal of Immunology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.4049/jimmunol.1402508

Restricted until

2037-12-31

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01_Flesch_Extent_of_systemic_spread_2015.pdf (682.41 KB)

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