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Strain dependence of diet-induced NASH and liver fibrosis in obese mice is linked to diabetes and inflammatory phenotype

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Authors

Farrell, Geoffrey
Mridha, Auvro
Yeh, Matthew
Arsov, Todor
Van Rooyen, Derrick
Brooling, John
Nguyen, Tori
Heydet, Deborah
Delghingaro-Augusto, Viviane
Nolan, Christopher

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Blackwell Publishing Inc.

Abstract

Background & Aims: Obese Alms1 mutant (foz/foz) NOD.B10 mice develop diabetes and fibrotic NASH when fed high-fat(HF) diet. To establish whether diabetes or obesity is more closely associated with NASH fibrosis, we compared diabetic foz/foz C57BL6/J with

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Liver International

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Restricted until

2037-12-31
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