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Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy?

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Date

2014

Authors

Luk, F
Bebawy, Mary
Callaghan, Richard

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Pharmacology and Experimental Therapeutics

Abstract

P-glycoprotein (P-gp) is a key player in the multidrug-resistant phenotype in cancer. The protein confers resistance by mediating the ATP-dependent efflux of an astonishing array of anticancer drugs. Its broad specificity has been the subject of numerous

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/23663

Collections

ANU Research Publications

Source

Drug Metabolism and Disposition

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1124/dmd.113.056176

Restricted until

2037-12-31

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01_Callaghan_Inhibition_of_the_multidrug_2014.pdf (176.98 KB)

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