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Evaluating vaccinia virus cytokine co-expression in TLR GKO mice

Date

Authors

Sutherland, Duncan

Regner, Matthias

Phipps, Simon

Matthaei, Klaus

Day, Stephanie

Ramshaw, Ian

Ranasinghe, Charani

Publisher

Blackwell Publishing Ltd

Abstract

Using Toll-like receptor (TLR) and MyD88 gene knock-out (GKO) mice the effect of TLRs and MyD88 on virus replication, interferon (IFN)-Β production, natural killer (NK) cell and CD8T cell responses were assessed following ectromelia virus (ECTV) and reco

Keywords

Keywords: beta interferon; interleukin 12; interleukin 2; myeloid differentiation factor 88; toll like receptor 2; toll like receptor 4; toll like receptor 7; toll like receptor 9; animal cell; animal experiment; animal model; animal tissue; antiviral activity; art cytokines; MyD88 -/-; pox-viruses; Toll-like receptors

URI

http://hdl.handle.net/1885/58970

Collections

ANU Research Publications

Source

Immunology and Cell Biology

Type

Journal article

DOI

10.1038/icb.2010.157

Restricted until

2037-12-31

Downloads

File

Description

01_Sutherland_Evaluating_vaccinia_virus_2010.pdf (594.76 KB)