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3D models of lamprey progesterone receptor complexed with progesterone, 7α-hydroxy-progesterone and 15α-hydroxy-progesterone

Date

Authors

Baker, Michael

Asnaashari, Paiyuam

Chang, David J.

McDonnell, Sunsanee

Publisher

Elsevier

Abstract

Sea lamprey, a basal vertebrate, contains a progesterone receptor [PR]. An unusual property of lamprey is that gonadotropin-releasing hormone induces synthesis of 15α-hydroxy-progesterone [15α-OH-P] instead of progesterone. There also is indirect eviden

Keywords

Keywords: 15alpha hydroxyprogesterone; hydroxyl group; hydroxyprogesterone; methionine; progesterone; progesterone receptor; unclassified drug; article; controlled study; hormone binding; hormone receptor interaction; human versus animal comparison; lamprey; protei Control of sea lamprey; Lamprey progesterone receptor; Progesterone receptor evolution

URI

http://hdl.handle.net/1885/65364

Collections

ANU Research Publications

Source

Steroids

Type

Journal article

DOI

10.1016/j.steroids.2010.10.008

Restricted until

2037-12-31

Downloads

File

Description

01_Baker_3D_models_of_lamprey_2011.pdf (1.52 MB)

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