3D models of lamprey progesterone receptor complexed with progesterone, 7α-hydroxy-progesterone and 15α-hydroxy-progesterone
Date
2011
Authors
Baker, Michael
Asnaashari, Paiyuam
Chang, David J.
McDonnell, Sunsanee
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Publisher
Elsevier
Abstract
Sea lamprey, a basal vertebrate, contains a progesterone receptor [PR]. An unusual property of lamprey is that gonadotropin-releasing hormone induces synthesis of 15α-hydroxy-progesterone [15α-OH-P] instead of progesterone. There also is indirect eviden
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Keywords
Keywords: 15alpha hydroxyprogesterone; hydroxyl group; hydroxyprogesterone; methionine; progesterone; progesterone receptor; unclassified drug; article; controlled study; hormone binding; hormone receptor interaction; human versus animal comparison; lamprey; protei Control of sea lamprey; Lamprey progesterone receptor; Progesterone receptor evolution
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Source
Steroids
Type
Journal article
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Restricted until
2037-12-31
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