Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

IMMUNOHISTOCHEMICAL LOCALIZATION AND ACTIVITY OF GLUTATHIONE TRANSFERASE ZETA (GSTZ1-1) IN RAT TISSUES

Date

Authors

Lantum, Hoffman

Baggs, Raymond

Krenitsky, Daria

Board, Philip

Anders, Michael

Publisher

American Society for Pharmacology and Experimental Therapeutics

Abstract

Glutathione transferase zeta (GSTZ1-1) catalyzes the biotransformation of a range of α-haloacids, including dichloroacetic acid (DCA), and the penultimate step in the tyrosine degradation pathway. DCA is a rodent carcinogen and a common drinking water co

Keywords

Keywords: acetic acid; acetone; alpha haloacid derivative; carcinogen; chlorofluoroacetic acid; dichloroacetic acid; drinking water; glutathione transferase; glutathione transferase zeta; haloacid; maleylacetone; tyrosine; unclassified drug; adrenal medulla; airway

URI

http://hdl.handle.net/1885/91063

Collections

ANU Research Publications

Source

Drug Metabolism and Disposition

Type

Journal article

DOI

10.1124/dmd.30.6.616

Restricted until

2037-12-31

Downloads

File

Description

01_Lantum_IMMUNOHISTOCHEMICAL_2002.pdf (775.88 KB)

02_Lantum_IMMUNOHISTOCHEMICAL_2002.pdf (903.01 KB)

abcd