Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization

Harada, Takaaki; Pham, Duc-Truc; Leung, Mandy HM; Ngo, Huy Tien; Lincoln, Stephen F; Easton, Christopher; Kee, Tak W

Cooperative binding and stabilization of the medicinal pigment curcumin by diamide linked γ-cyclodextrin dimers: a spectroscopic characterization

Date

2011

Authors

Harada, Takaaki

Pham, Duc-Truc

Leung, Mandy HM

Ngo, Huy Tien

Lincoln, Stephen F

Easton, Christopher

Kee, Tak W

Publisher

American Chemical Society

Abstract

Diamide linked γ-cyclodextrin (γ-CD) dimers are used to capture curcumin and suppress its decomposition in water. In this study, succinamide and urea linked γ-CD dimers joined through the C6A carbon on each γ-CD are used. The γ-CD dimers, 66γCD2su a