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N-Acetylcysteine prevents but does not reverse dexamethasone-induced hypertension

Date

Authors

Krug, Susanne

Zhang, Yi

Mori, Trevor A

Croft, Kevin D

Vickers, Janine

Langton, Leanne

Whitworth, Judith

Publisher

Blackwell Science Asia

Abstract

1. We have shown previously that N-acetylcysteine (NAC) prevents the increase in blood pressure induced by adrenocorticotropin treatment. The present study investigated the effect of NAC on dexamethasone (Dex)-induced hypertension. 2. Male Sprague-Dawley

Keywords

Keywords: acetylcysteine; dexamethasone; isoprostane derivative; nitric oxide; sodium chloride; animal experiment; animal model; article; blood pressure measurement; controlled study; drug mechanism; fluid intake; food intake; hypertension; male; metabolism; nonhum Dexamethasone; Hypertension; N-acetylcysteine; Oxidative stress

URI

http://hdl.handle.net/1885/23424

Collections

ANU Research Publications

Source

Clinical and Experimental Pharmacology and Physiology

Type

Journal article

DOI

10.1111/j.1440-1681.2008.04947.x

Restricted until

2037-12-31

Downloads

File

Description

01_Krug_N-Acetylcysteine_prevents_but_2008.pdf (99.3 KB)