Oxidation of threonine residues with IBX reagents

Date

Authors

Manohari Abeysinghe, P
Han, Yu
Harding, Margaret

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

The treatment of protected Thr peptides with excess polymer-bound IBX effects sequential oxidation of the Thr secondary alcohol to the ketone, followed by hydroxylation of the alpha carbon of the Thr residues with loss of stereochemistry at this position.

Description

Citation

Source

Tetrahedron Letters

Book Title

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Restricted until

2037-12-31