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Adenosine and Forskolin Inhibit Platelet Aggregation by Collagen but not the Proximal Signalling Events

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Authors

Clark, Joanne C.
Kavanagh, Deirdre M.
Watson, Stephanie K
Pike, Jeremy A.
Andrews, Robert K
Gardiner, Elizabeth
Poulter, N. S.
Hill, Stephen J.
Watson, Steve P

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Volume Title

Publisher

Thieme Publishing

Abstract

Background The G protein-coupled receptor, adenosine A2A, signals through the stimulatory G protein, Gs, in platelets leading to activation of adenylyl cyclase and elevation of cyclic adenosine monophosphate (cAMP) and inhibition of platelet activation.

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Citation

Source

Thrombosis and Haemostasis

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Restricted until

2037-12-31
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