Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

Potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase

Thumbnail Image

Date

2011

Authors

Cao, Feihua (Lucy)
Gamble, Allan
Kim, Hye-Kyung
Onagi, Hideki
Gresser, Mary
Kerr, Jamie
Easton, Christopher

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

Fatty acid glycolates are nanomolar inhibitors of small cell lung carcinoma peptidylglycine α-amidating monooxygenase, with binding affinities orders of magnitude stronger than those of the analogous thioesters, the corresponding substrate glycine deriva

Description

Keywords

Keywords: alpha amidating enzyme; alpha amidating enzyme inhibitor; glycine derivative; oxygenase inhibitor; procalcitonin; thioester; unclassified drug; article; binding affinity; cancer cell culture; controlled study; drug potency; drug selectivity; enzyme inhibi

Citation

URI

http://hdl.handle.net/1885/59329

Collections

ANU Research Publications

Source

MedChemComm

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1039/c1md00079a

Restricted until

2037-12-31

Downloads

File
Description
01_Cao_Potent_and_selective_2011.pdf (90.98 KB)

DSpace software copyright © 2002-2026 LYRASIS