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Antiphospholipid antibodies and stroke in Down syndrome

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dc.contributor.authorGatenby, Paul
dc.contributor.authorTuck, Roger
dc.contributor.authorAndrews, C
dc.contributor.authorO'Neil, R
dc.date.accessioned2015-12-13T22:36:58Z
dc.date.available2015-12-13T22:36:58Z
dc.date.issued2003
dc.date.updated2015-12-11T09:34:26Z
dc.description.abstractTwo patients with Down syndrome and the primary antiphospholipid antibody are described. One patient had a vasculopathy similar to that previously described as Moyamoya. Down syndrome is characterized by immune defects including a tendency to autoimmune phenomena. This report extends the scope of these observations and particularly draws out the potential role of antiphospholipid antibodies. Indeed antiphospholipid antibodies may well explain the well-known association of Down syndrome and stroke.
dc.identifier.issn0961-2033
dc.identifier.urihttp://hdl.handle.net/1885/77027
dc.publisherArnold Publishers
dc.sourceLUPUS
dc.subjectKeywords: phospholipid antibody; adult; article; autoimmunity; case report; computer assisted tomography; disease association; Down syndrome; female; human; magnetic resonance angiography; moyamoya disease; nuclear magnetic resonance imaging; priority journal; stro Antiphospholipid syndrome; Down syndrome; Moyamoya; Stroke
dc.titleAntiphospholipid antibodies and stroke in Down syndrome
dc.typeJournal article
local.bibliographicCitation.lastpage62
local.bibliographicCitation.startpage58
local.contributor.affiliationGatenby, Paul, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationTuck, Roger, Princess Alexandra Hospital
local.contributor.affiliationAndrews, C, University of Sydney
local.contributor.affiliationO'Neil, R, University of Sydney
local.contributor.authoruidGatenby, Paul, u4044018
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor110703 - Autoimmunity
local.identifier.ariespublicationMigratedxPub5873
local.identifier.citationvolume12
local.identifier.doi10.1191/0961203303lu240cr
local.identifier.scopusID2-s2.0-0037262896
local.type.statusPublished Version

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