Complement Contributes to Inflammatory Tissue Destruction in a Mouse Model of Ross River Virus-Induced Disease

Morrison, Thomas E.; Fraser, Robert J; Smith, Paul; Mahalingam, Suresh (Surendran); Heise, Mark T

Complement Contributes to Inflammatory Tissue Destruction in a Mouse Model of Ross River Virus-Induced Disease

Date

2007

Authors

Morrison, Thomas E.

Fraser, Robert J

Smith, Paul

Mahalingam, Suresh (Surendran)

Heise, Mark T

Publisher

American Society for Microbiology

Abstract

Arthritogenic alphaviruses, including Ross River virus (RRV) and chikungunya virus, are mosquito-borne viruses that cause significant human disease worldwide, including explosive epidemics that can result in thousands to millions of infected individuals.