A cell autonomous role for the Notch ligand Delta-like 3 in αβ T-cell development

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Hoyne, Gerard
Chapman, Gavin
Sontani, Yovina
Pursglove, Sharon E.
Dunwoodie, Sally

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Blackwell Publishing Ltd

Abstract

Notch signalling is critical to help direct T-cell lineage commitment in early T-cell progenitors and in the development of αΒ T-cells. Epithelial and stromal cell populations in the thymus express the Notch DSL (Delta, Serrate and Lag2)ligands Delta-li

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Immunology and Cell Biology

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Restricted until

2037-12-31