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Isochromophilone IX,a Novel GABA-Containing Metabolite Isolated from a Cultured Fungus Penicillium sp.

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Date

2003

Authors

Michael, Adam
Grace, Emily
Kotiw, Michael
Barrow, Russell

Journal Title

Journal ISSN

Volume Title

Publisher

CSIRO Publishing

Abstract

Isochromophilone IX, a novel antibiotic active component was isolated from a penicillium species and investigated. Isochromophilone IX displays a specific rotation with the same sign as isochromophilone VI. It was found that isochromophilone represents the first occurrence of an γ-amino butyric acid (GABA) containing metabolite among only four naturally occuring members of this structure class.

Description

Keywords

Keywords: Amino acids; Fungi; High performance liquid chromatography; Isomers; Mass spectrometry; Metabolites; Correlated spectroscopy (COSY); Antibiotics

Citation

URI

http://hdl.handle.net/1885/88486

Collections

ANU Research Publications

Source

Australian Journal of Chemistry

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1071/CH02021

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