Altered inhibitory synaptic transmission in superficial dorsal horn neurones in spastic and oscillator mice
Date
2003
Authors
Graham, B.A.
Schofield, P.R.
Sah, Pankaj
Callister, R.J.
Journal Title
Journal ISSN
Volume Title
Publisher
Cambridge University Press
Abstract
The spastic (spa) and oscillator (ot) mouse have naturally occurring mutations in the inhibitory glycine receptor (GlyR) and exhibit severe motor disturbances when exposed to unexpected sensory stimuli. We examined the effects of the spa and ot mutations
Description
Keywords
Keywords: 4 aminobutyric acid A receptor; glycine receptor; animal cell; animal tissue; controlled study; disease severity; exposure; female; GABAergic transmission; gene mutation; genotype; inhibition kinetics; inhibitory postsynaptic potential; male; motor dysfun
Citation
Collections
Source
Journal of Physiology
Type
Journal article