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B cell clones that sustain long-term plasmablast growth in T-independent extrafollicular antibody responses

Date

Authors

Hsu, M-C.

Toellner, K-M.

Garcia De Vinuesa, Maria Carola

MacLennan, Ian C. M.

Publisher

National Academy of Sciences (USA)

Abstract

Some antigens induce Ab responses without T lymphocyte help. Among these, many polysaccharide-based antigens cause marginal zone B cells to proliferate and differentiate into plasma cells. B1 cells also respond to some of these antigens. In this article,

Keywords

(4 hydroxy 3 nitrophenyl)acetylficoll, acetic acid derivative, antigen, benzene derivative, CD3 antigen, ficoll, hydroxyl group, immunoglobulin D, immunoglobulin G3, immunoglobulin M, nitro derivative, RAG1 protein, unclassified drug, animal cell, animal B1 cells, Memory, Plasmablasts

URI

http://hdl.handle.net/1885/20922

Collections

ANU Research Publications

Source

PNAS - Proceedings of the National Academy of Sciences of the United States of America

Type

Journal article

DOI

10.1073/pnas.0601502103

Restricted until

2037-12-31

Downloads

File

Description

01_Hsu_B_cell_clones_that_sustain_2006.pdf (1.85 MB)