Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice

Date

2003

Authors

Drago, John
McColl, Craig
Horne, M
Finkelstein, D I
Ross, S A

Journal Title

Journal ISSN

Volume Title

Publisher

Birkhauser Verlag

Abstract

Neuronal nicotinic acetylcholine receptors are ligand-gated ion channels that subserve a range of functions in the brain and peripheral nervous system. They are pentamers variously composed of a (a2-at0) and/3 subunits (β2-β4). Pharmacological and ligan

Description

Keywords

Keywords: acetylcholine; neuronal nicotinic receptor; nicotinic receptor; receptor subunit; unclassified drug; anxiety; autonomic nervous system; dopaminergic transmission; knockout gene; knockout mouse; learning; locomotion; memory; mouse; nerve cell; neurotransmi Acetylcholine; Knockin; Knockout; Nicotinic; Subunits; Transgenic

Citation

Source

Cellular and Molecular Life Sciences

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1007/s00018-003-2259-9

Restricted until