Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice

Drago, John; McColl, Craig; Horne, M; Finkelstein, D I; Ross, S A

Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice

Date

2003

Authors

Drago, John

McColl, Craig

Horne, M

Finkelstein, D I

Ross, S A

Publisher

Birkhauser Verlag

Abstract

Neuronal nicotinic acetylcholine receptors are ligand-gated ion channels that subserve a range of functions in the brain and peripheral nervous system. They are pentamers variously composed of a (a2-at0) and/3 subunits (β2-β4). Pharmacological and ligan