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Neuronal nicotinic receptors: insights gained from gene knockout and knockin mutant mice

Date

Authors

Drago, John

McColl, Craig

Horne, M

Finkelstein, D I

Ross, S A

Publisher

Birkhauser Verlag

Abstract

Neuronal nicotinic acetylcholine receptors are ligand-gated ion channels that subserve a range of functions in the brain and peripheral nervous system. They are pentamers variously composed of a (a2-at0) and/3 subunits (β2-β4). Pharmacological and ligan

Keywords

Keywords: acetylcholine; neuronal nicotinic receptor; nicotinic receptor; receptor subunit; unclassified drug; anxiety; autonomic nervous system; dopaminergic transmission; knockout gene; knockout mouse; learning; locomotion; memory; mouse; nerve cell; neurotransmi Acetylcholine; Knockin; Knockout; Nicotinic; Subunits; Transgenic

URI

http://hdl.handle.net/1885/78305

Collections

ANU Research Publications

Source

Cellular and Molecular Life Sciences

Type

Journal article

DOI

10.1007/s00018-003-2259-9

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