Construction and evaluation of live attenuated myxoma virus vaccines with targeted virulence gene deletions

Date

2008

Authors

Adams, Mathew
van Leeuwen, Barbara
Kerr, P J

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

Three deletion mutant viruses were constructed as potential vaccines against myxomatosis using the naturally attenuated Uriarra strain of myxoma virus. The viruses had the M007 (encodes a secreted γ-interferon receptor homologue), M010 (encodes an epider

Description

Keywords

Keywords: epidermal growth factor; gamma interferon receptor; inhibitor of apoptosis protein; live vaccine; Myxoma virus Ur delta m007 vaccine; Myxoma virus Ur delta m10 m11 vaccine; Myxoma virus Ur triple gene knockout vaccine; unclassified drug; animal cell; anim Myxoma virus; Myxomatosis; Poxvirus; Vaccine

Citation

Source

Vaccine

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31
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