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Repeated antidepressant therapy increases cyclic GMP signaling in rat hippocampus

Date

Authors

Reierson, Gillian W.

Mastronardi, Claudio

Licinio, Julio

Wong, Ma-Li

Publisher

Elsevier

Abstract

Cyclic adenosine monophosphpate (cAMP) signaling is thought to be involved in the pathophysiology of major depressive disorder and antidepressant action; however, relatively little is known about the possible role of cyclic guanosine monophosphate (cGMP)

Keywords

Keywords: amitriptyline; antidepressant agent; cyclic GMP; fluoxetine; phosphodiesterase; animal experiment; animal tissue; article; controlled study; drug effect; drug efficacy; drug mechanism; gene expression; hippocampus; male; nonhuman; nucleotide sequence; pri Antidepressant; Cyclic; Hippocampus; Nucleotides; Phosphodiesterase; Rat

URI

http://hdl.handle.net/1885/35270

Collections

ANU Research Publications

Source

Neuroscience Letters

Type

Journal article

DOI

10.1016/j.neulet.2009.09.047

Restricted until

2037-12-31

Downloads

File

Description

01_Reierson_Repeated_antidepressant_2009.pdf (375.47 KB)

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