Pharmacogenetic Impact of VKORC1 and CYP2C9 allelic variants on warfarin dose requirements in a hispanic population isolate

Date

2010

Authors

Palacio, L. G.
Falla, D.
Tobon, I.
Mejia, F.
Lewis, J. E.
Martinez, A. F.
Arcos-Burgos, Mauricio
Camargo, Mauricio

Journal Title

Journal ISSN

Volume Title

Publisher

SAGE Publications

Abstract

Warfarin is the most prescribed oral anticoagulant worldwide. Because of the complexity of warfarin therapy, we attempted to dissect genetic from bioenvironmental factors influencing warfarin dose responses in individuals of a genetic isolate of Hispanic

Description

Keywords

Keywords: warfarin; adult; age; allele; artery thrombosis; article; controlled study; CYP2C9 gene; deep vein thrombosis; environmental factor; female; gene; gene interaction; genetic polymorphism; genetic variability; genotype; genotype environment interaction; His Colombia; CYP2C9; Genetic isolate; Pharmacogenetics; VKORC1; Warfarin

Citation

Source

Clinical and Applied Thrombosis/Hemostasis

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31