Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

A role for the 2 residue in the second transmembrane helix of the GABA A receptor gamma2S subunit in channel conductance and gating

Date

Authors

Luu, Tien

Cromer, Brett A

Gage, Peter

Tierney, Mary (Louise)

Publisher

Springer

Abstract

GABAA receptors composed of α, β and γ subunits display a significantly higher single-channel conductance than receptors comprised of only α and β subunits. The pore of GABAA receptors is lined by the second transmembrane region from each of its five

Keywords

Keywords: 4 aminobutyric acid A receptor; serine; 4 aminobutyric acid A receptor; animal cell; article; channel gating; conductance; depolarization; ion conductance; kinetics; membrane conductance; membrane transport; mouse; nonhuman; transport kinetics; wild type; Conductance; GABA; Gamma subunit; Gating; Kinetics; Single-channel

URI

http://hdl.handle.net/1885/73903

Collections

ANU Research Publications

Source

Journal of Membrane Biology

Type

Journal article

DOI

10.1007/s00232-005-0759-2

Restricted until

2037-12-31

Downloads

File

Description

01_Luu_A_role_for_the_2_residue_in_2005.pdf (304.74 KB)