Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

The antioxidant tempol prevents and partially reverses dexamethasone-induced hypertension in the rat

Date

Authors

Zhang, Yi

Croft, Kevin D

Mori, Trevor A

Schyvens, Chris

McKenzie, Katja

Whitworth, Judith

Publisher

Elsevier

Abstract

Background: Many forms of hypertension are associated with increased oxidative stress. This study investigated the effects of Tempol, a superoxide scavenger, on prevention and reversal of hypertension induced by the synthetic glucocorticoid dexamethasone

Keywords

Keywords: antioxidant; dexamethasone; drinking water; glucocorticoid; isoprostane; tempol; animal experiment; animal model; animal tissue; article; controlled study; hypertension; male; nonhuman; oxidative stress; plasma; priority journal; rat; systolic blood press Dexamethasone; F2-isoprostanes; Hypertension; Oxidative stress; Tempol

URI

http://hdl.handle.net/1885/78216

Collections

ANU Research Publications

Source

American Journal of Hypertension

Type

Journal article

DOI

10.1016/j.amjhyper.2003.11.004