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N-Acetylcysteine Antagonizes the Development But Does Not Reverse ACTH-Induced Hypertension in the Rat

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Date

2006

Authors

Mondo, Charles K
Zhang, Yi
De Macedo Possamai, Vinicius
Miao, Yuchun
Schyvens, Chris
McKenzie, Katja
Hu, Lexian
Guo, Zhijun
Whitworth, Judith

Journal Title

Journal ISSN

Volume Title

Publisher

Informa Healthcare

Abstract

We investigated the effect of antioxidant N-acetylcysteine (NAC) on adrenocorticotropic hormone (ACTH)-hypertension, Male Sprague-Dawley rats received NAC (10 mg/L) or water 4 days before ACTH/saline treatment for 13 days (prevention study). In a reversal

Description

Keywords

Keywords: acetylcysteine; corticotropin; sodium chloride; animal model; article; controlled study; drug effect; fluid intake; hypertension; male; nonhuman; rat; systolic blood pressure; Acetylcysteine; Adrenocorticotropic Hormone; Animals; Blood Pressure; Disease M Adrenocorticotropic hormone; Blood pressure; N-acetylcysteine; Rat

Citation

URI

http://hdl.handle.net/1885/18258

Collections

ANU Research Publications

Source

Clinical and Experimental Hypertension

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1080/10641960500468219

Restricted until

2037-12-31

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01_Mondo_N-Acetylcysteine_Antagonizes_2006.pdf (114.98 KB)

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