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The marsupial CD8 gene locus: Molecular cloning and expression analysis of the alpha and beta sequences in the gray short-tailed opossum (Monodelphis domestica) and the tammar wallaby (Macropus eugenii)

Date

Authors

Duncan, Louise G.

Nair, Sham V.

Deane, Elizabeth

Publisher

Elsevier

Abstract

In eutherian mammals, CD8 is a key receptor of cytotoxic T cells and plays a pivotal role in the recognition and elimination of infected host cells by cell-mediated cytotoxicity. Here, we report the molecular cloning and expression analysis of CD8α and C

Keywords

Keywords: amino acid; CD8alpha antigen; complementary DNA; cysteine; disulfide; protein p56; alpha chain; article; cell subpopulation; cytoplasm; dimerization; disulfide bond; gene expression; gene locus; gene sequence; genetic transcription; lymphoid tissue; marsu CD8; cDNA cloning; Cell-mediated immunity; Cytotoxic T lymphocytes; Gene structure; Marsupial; Opossum; Tammar

URI

http://hdl.handle.net/1885/59742

Collections

ANU Research Publications

Source

Veterinary Immunology and Immunopathology

Type

Journal article

DOI

10.1016/j.vetimm.2008.12.003

Restricted until

2037-12-31

Downloads

File

Description

01_Duncan_The_marsupial_CD8_gene_locus:_2009.pdf (2.54 MB)