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Identification of Key Beta Cell Gene Signaling Pathways Involved in Type 1 Diabetes

Date

Authors

Silva, Diego

Petrovsky, Nikolai

Publisher

New York Academy of Sciences

Abstract

In type 1 diabetes, β cells die through a process of immune-mediated apoptosis. To better understand this process, it has been accepted practice to study β cell or islet apoptosis in vitro in response to a range of immune stimuli, such as interferon gam

Keywords

Keywords: free radical; gamma interferon; interleukin 1; interleukin 1beta; nitric oxide; adolescent; animal cell; animal model; apoptosis; cell destruction; cell immortalization; cell isolation; cell line; conference paper; cytokine production; gene expression; im Apoptosis; Beta cell; Cytokines; Gene regulation; Type 1 diabetes

URI

http://hdl.handle.net/1885/86028

Collections

ANU Research Publications

Source

Annals of the New York Academy of Sciences

Type

Journal article

DOI

10.1196/annals.1337.033

Restricted until

2037-12-31

Downloads

File

Description

01_Silva_Identification_of_Key_Beta_2004.pdf (86.47 KB)

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