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Association of a functional polymorphism of the monoamine oxdiase A gene promoter with personality and psychiatric symptoms

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Date

2000

Authors

Jorm, Anthony F
Henderson, A Scott
Jacomb, Trish
Christensen, Helen
Korten, Ailsa
Tan, Susan (Xiaoyun)
Easteal, Simon
Rodgers, Bryan

Journal Title

Journal ISSN

Volume Title

Publisher

Lippincott Williams & Wilkins

Abstract

A functional polymorphism in the promoter of the monoamine oxidase gene has recently been described by Sabol et al. This polymorphism is a strong candidate for associations with personality traits and psychiatric symptoms. We report relevant data from a general population sample of 850 Caucasian Australians. We found no associations with anxiety and depression symptoms, with personality traits that predispose to anxiety (neuroticism, behavioral inhibition, negative affect) or to a personality trait related to antisocial behavior (psychoticism). (C) 2000 Lippincott Williams and Wilkins.

Description

Keywords

Keywords: amine oxidase (flavin containing) isoenzyme A; adolescent; adult; affect; antisocial behavior; anxiety; article; Australia; Caucasian; depression; female; genetic association; genetic polymorphism; human; major clinical study; male; mental disease; neuros Alcohol abuse; Anxiety; Depression; Extraversion; Genetics; Monoamine oxidase A; Neuroticism; Psychoticism

Citation

URI

http://hdl.handle.net/1885/90293

Collections

ANU Research Publications

Source

Psychiatric Genetics

Type

Journal article

Book Title

Entity type

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DOI

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