Stereoselective Total Synthesis of the Nonenolide (+)-Microcarpalide

Banwell, Martin; Loong, David

Stereoselective Total Synthesis of the Nonenolide (+)-Microcarpalide

Date

2004

Authors

Banwell, Martin

Loong, David

Publisher

Elsevier

Abstract

The enantiomer [(+)-1] of the nonenolide natural product microcarpalide [(-)-1] has been prepared from (S)-malic acid (3) and 3-decyn-1-ol (11) via a sixteen step sequence involving, inter alia, two metathesis processes.

Keywords

Keywords: malic acid; microcarpalide; natural product; nonenolide; unclassified drug; article; carbon nuclear magnetic resonance; drug synthesis; enantiomer; reaction analysis; stereochemistry

URI

http://hdl.handle.net/1885/78446

Collections

ANU Research Publications

Source

Heterocycles

Type

Journal article

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Stereoselective Total Synthesis of the Nonenolide (+)-Microcarpalide

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