An elasto-hydrodynamical model of friction for the locomotion of Caenorhabditis elegans

dc.contributor.authorSauvage, P
dc.contributor.authorArgentina, Médéric
dc.contributor.authorDrappier, J
dc.contributor.authorSenden, Timothy
dc.contributor.authorSiméon, J
dc.contributor.authorDi Meglio, Jean-Marc
dc.date.accessioned2015-12-10T22:53:33Z
dc.date.issued2011
dc.date.updated2016-02-24T11:56:08Z
dc.description.abstractCaenorhabditis elegans (C. elegans) is one of the most studied organisms by biologists. Composed of around one thousand cells, easy to culture and to modify genetically, it is a good model system to address fundamental physiological questions and in particular to investigate neuromuscular processes. Many C. elegans mutants can be distinguished by their locomotion phenotype and it then important to understand the biomechanics of their locomotion and in particular the mechanics of their undulating crawling motion on agar aqueous gels where they are commonly grown and observed. In this article, we present a mechanical model of the friction of the worms on their substrate where we have included capillarity (which pins the worm of the gel), the hydrodynamics of the lubrication film (between worm and gel) and the substrate/body elasticity. We determine the ratio of the transverse to longitudinal friction coefficients of the worm body on the culture gel as a function of a control parameter which describes the relative role of the deformation of the gel and the viscous dissipation in the lubrication film. Experimentally this ratio is - for soft gels - larger than the maximal value predicted by our model (this maximum is equal to 2, the value for an infinite cylinder in bulk liquid) and we propose to include the plasticity of the gel (i.e. the dissipation of the deformation of the gel) for a better description of the worm/gel interaction.
dc.identifier.issn0021-9290
dc.identifier.urihttp://hdl.handle.net/1885/59399
dc.publisherElsevier
dc.sourceJournal of Biomechanics
dc.subjectKeywords: Bulk liquid; Caenorhabditis elegans; Control parameters; Elegans; Friction coefficients; Hydrodynamical model; Infinite cylinders; Locomotion; Lubrication films; Maximal values; Mechanical model; Model system; Soft gels; Undulation; Viscous dissipation; W C. elegans; Friction; Locomotion; Undulation; Worm
dc.titleAn elasto-hydrodynamical model of friction for the locomotion of Caenorhabditis elegans
dc.typeJournal article
local.bibliographicCitation.issue6
local.bibliographicCitation.lastpage1122
local.bibliographicCitation.startpage1117
local.contributor.affiliationSauvage, P, UMR 7057 CNRS
local.contributor.affiliationArgentina, Médéric, UMR 7057 CNRS, Université Paris Diderot
local.contributor.affiliationDrappier, J, Laboratoire Matière et Systèmes Complexes
local.contributor.affiliationSenden, Timothy , College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationSiméon, J, Laboratoire Matière et Systèmes Complexes
local.contributor.affiliationDi Meglio, Jean-Marc, Physicio-Chimique
local.contributor.authoremailu8612475@anu.edu.au
local.contributor.authoruidSenden, Timothy , u8612475
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor060601 - Animal Physiology - Biophysics
local.identifier.absfor020405 - Soft Condensed Matter
local.identifier.absseo961199 - Physical and Chemical Conditions of Water not elsewhere classified
local.identifier.ariespublicationu9210271xPUB488
local.identifier.citationvolume44
local.identifier.doi10.1016/j.jbiomech.2011.01.026
local.identifier.scopusID2-s2.0-79953025501
local.identifier.thomsonID000290187500020
local.identifier.uidSubmittedByu9210271
local.type.statusPublished Version

Downloads

Original bundle

Now showing 1 - 1 of 1
No Thumbnail Available
Name:
01_Sauvage_An_elasto-hydrodynamical_model_2011.pdf
Size:
478.13 KB
Format:
Adobe Portable Document Format
Back to topicon-arrow-up-solid
 
APRU
IARU
 
edX
Group of Eight Member

Acknowledgement of Country

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.


Contact ANUCopyrightDisclaimerPrivacyFreedom of Information

+61 2 6125 5111 The Australian National University, Canberra

TEQSA Provider ID: PRV12002 (Australian University) CRICOS Provider Code: 00120C ABN: 52 234 063 906