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Activation of ±2A adrenoceptors alters dendritic spine development and the expression of spinophilin in cultured cortical neurons

Date

Authors

Hu, Jingyao

Vidovic, Maria

Chen, Ming-Ming

Lu, Qun-Ying

Song, Zan-Min

Publisher

Elsevier

Abstract

α2 adrenoceptors have been shown to regulate the development of dendrites in mammalian cortical neurones. In this study we have investigated how agonists of α2 adrenoceptors affect length and density of dendritic spines in cultured cortical neurones fro

Keywords

Keywords: 2 (1 methyl 2 isoindolinylmethyl) 2 imidazoline; 2 (2 methoxy 1,4 benzodioxan 2 yl) 2 imidazoline; adrenergic receptor; alpha 2 adrenergic receptor blocking agent; alpha 2 adrenergic receptor stimulating agent; alpha 2A adrenergic receptor; brimonidine; c C57/B6 mice; Cultured neurone; Cytoskeleton; Neurotransmitter receptor; Phosphorylation

URI

http://hdl.handle.net/1885/21105

Collections

ANU Research Publications

Source

Brain Research

Type

Journal article

DOI

10.1016/j.brainres.2007.12.073

Restricted until

2037-12-31

Downloads

File

Description

01_Hu_Activation_of_±2A_2008.pdf (806.91 KB)