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Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

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Date

2003

Authors

Banwell, Martin
Edwards, Alison
Jolliffe, Katrina
Smith, Jason A
Hamel, Ernest
Verdier-Pinard, Pascal

Journal Title

Journal ISSN

Volume Title

Publisher

Royal Society of Chemistry

Abstract

The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.

Description

Keywords

Keywords: Addition reactions; Alcohols; Hydrogenation; Molecular structure; Negative ions; Olefins; Single crystals; Substitution reactions; Synthesis (chemical); X ray analysis; Bromination; Deprotonation; Electrocyclic ring-opening reaction; Gem-dibromocyclopropa

Citation

URI

http://hdl.handle.net/1885/85802

Collections

ANU Research Publications

Source

Organic and Biomolecular Chemistry

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1039/b209992f

Restricted until

2037-12-31

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01_Banwell_Total_synthesis_of_2003.pdf (265.59 KB)

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