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Global Phosphoproteomics Identifies a Major Role for AKT and 14-3-3 in Regulating EDC3

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Date

2010

Authors

Larance, Mark
Rowland, Alexander F
Loehn, Kyle L
Humphreys, David T
Preiss, Thomas
Guilhaus, Michael
James, David E

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Biochemistry and Molecular Biology Inc

Abstract

Insulin plays an essential role in metabolic homeostasis in mammals, and many of the underlying biochemical pathways are regulated via the canonical phosphatidylinositol 3-kinase/AKT pathway. To identify novel metabolic actions of insulin, we conducted a

Description

Keywords

Keywords: binding protein; insulin; messenger RNA; protein kinase B; serine; animal cell; animal tissue; article; downstream processing; human; human cell; mouse; nonhuman; nucleotide sequence; priority journal; protein analysis; protein phosphorylation; protein pr

Citation

URI

http://hdl.handle.net/1885/52113

Collections

ANU Research Publications

Source

Molecular and Cellular Proteomics

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1074/mcp.M900435-MCP200

Restricted until

2037-12-31

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Description
01_Larance_Global_Phosphoproteomics_2010.pdf (1.5 MB)

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