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Uptake of wetting method in Africa to reduce cyanide poisoning and konzo from cassava

dc.contributor.authorBradbury, James
dc.contributor.authorCliff, Julie
dc.contributor.authorDenton, Ian
dc.date.accessioned2015-12-10T22:56:14Z
dc.date.issued2011
dc.date.updated2016-02-24T08:30:14Z
dc.description.abstractCassava contains cyanogenic glucosides which are hydrolysed by an enzyme linamarase to produce cyanohydrins which breakdown to toxic cyanide. Cyanide ingestion from bitter cassava can cause cyanide poisoning sometimes leading to death and also konzo, an irreversible paralysis of the legs which occurs mainly in children and young women. In 2005 we developed a simple wetting method that reduces the total cyanide content of cassava flour 3-6-fold. It involves wetting the flour, spreading it in a thin layer in the shade for 5. h and using it the same day to make traditional thick porridge (ugali). The method was readily accepted by rural women and requires no additional equipment or water. Laminated, illustrated posters describing the method are available for free in ten languages, see http://online.anu.edu.au/BoZo/CCDN/. An equally effective treatment method is to expose wet flour in a thin layer in the sun for 2. h. Projects for rehabilitation and prevention of konzo occurred in Mozambique in 2007 and in 2008-2009 in Tanzania, funded by AusAID. The Ministry of Health in Mozambique is now using our posters in Macua. In Uvira DRC, the wetting method has been taught in many villages and over 1200 posters distributed.
dc.identifier.issn0278-6915
dc.identifier.urihttp://hdl.handle.net/1885/60168
dc.publisherPergamon Press
dc.sourceFood and Chemical Toxicology
dc.subjectKeywords: cyanide; water; Africa; article; bitter taste; cassava; flour; food intake; food poisoning; food processing; human; konzo; mortality; rehabilitation care; rural area; wetting method; Africa; beta-Glucosidase; Cameroon; Consumer Health Information; Cyanide Cassava; Cyanide poisoning; Cyanogenic glucosides; Konzo; Wetting method
dc.titleUptake of wetting method in Africa to reduce cyanide poisoning and konzo from cassava
dc.typeJournal article
local.bibliographicCitation.issueonline 25 May 2010
local.bibliographicCitation.lastpage542
local.bibliographicCitation.startpage539
local.contributor.affiliationBradbury, James, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationCliff, Julie, Universidade Eduardo Mondlane
local.contributor.affiliationDenton, Ian, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidBradbury, James, u4023610
local.contributor.authoruidDenton, Ian, v007419
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.identifier.absfor110101 - Medical Biochemistry: Amino Acids and Metabolites
local.identifier.absseo920406 - Food Safety
local.identifier.absseo920411 - Nutrition
local.identifier.ariespublicationf2965xPUB526
local.identifier.citationvolume49
local.identifier.doi10.1016/j.fct.2010.04.049
local.identifier.scopusID2-s2.0-79551585391
local.type.statusPublished Version

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