Discriminating microbe from self suffers a double toll

Date

2006

Authors

Goodnow, Christopher

Journal Title

Journal ISSN

Volume Title

Publisher

American Association for the Advancement of Science

Abstract

The autoimmune disease lupus is caused by immune cells that secrete antibodies to the patient's own antigens. A mouse version of the disease reveals two genes that lead to this disregulation.

Description

Keywords

Keywords: Antibodies; Antigens; Cells; Diseases; Genes; Immunology; Autoimmune disease; Disregulation; Lupus; Mouse version; Microorganisms; B lymphocyte receptor; DNA; immunoglobulin G; ribonucleoprotein; RNA; single stranded RNA; T lymphocyte receptor; toll like

Citation

URI

http://hdl.handle.net/1885/92341

Collections

ANU Research Publications

Source

Science

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1126/science.1129797

Restricted until

2037-12-31

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Description
01_Goodnow_Discriminating_microbe_from_2006.pdf (450.44 KB)

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