Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats

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Lamontagne, Julien
Masiello, Pellegrino
Marcil, Mariannick
Delghingaro-Augusto, Viviane
Burelle, Yan
Prentki, Marc
Nolan, Christopher

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National Research Council of Canada

Abstract

Deteriorating islet β-cell function is key in the progression of an impaired glucose tolerance state to overt type 2 diabetes (T2D), a transition that can be delayed by exercise. We have previously shown that trained rats are protected from heart ischemi

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Applied Physiology, Nutrition and Metabolism

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