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Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats

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Date

2007

Authors

Lamontagne, Julien
Masiello, Pellegrino
Marcil, Mariannick
Delghingaro-Augusto, Viviane
Burelle, Yan
Prentki, Marc
Nolan, Christopher

Journal Title

Journal ISSN

Volume Title

Publisher

National Research Council of Canada

Abstract

Deteriorating islet β-cell function is key in the progression of an impaired glucose tolerance state to overt type 2 diabetes (T2D), a transition that can be delayed by exercise. We have previously shown that trained rats are protected from heart ischemi

Description

Keywords

Keywords: fatty acid; insulin; lipid; amino acid sequence; analysis of variance; animal; animal experiment; article; blood; female; genetics; lipid metabolism; metabolism; molecular genetics; pancreas islet; polymerase chain reaction; rat; Sprague Dawley rat; Amino Fatty-acid oxidation; Free fatty acids; Islet ß-cell; Lipid metabolism genes; Lipid partitioning

Citation

URI

http://hdl.handle.net/1885/29544

Collections

ANU Research Publications

Source

Applied Physiology, Nutrition and Metabolism

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1139/H06-105

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