The Role of P2Y 1 Purinergic Receptors and Cytosolic Ca2 + Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line
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Junankar, Pauline
Karjalainen, Ari
Kirk, Kiaran
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American Society for Biochemistry and Molecular Biology Inc
Abstract
Exposure of HTC rat hepatoma cells to a 33% decrease in extracellular osmolality caused the cytosolic Ca2+ concentration ([Ca2+]i) to increase transiently by ∼90 nM. This rise in [Ca2+]i was inhibited strongly by apyrase, grade VII (which has a low ATP/
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Journal of Biological Chemistry
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2037-12-31