Cultural advice

The Australian National University acknowledges, celebrates and pays our respects to the Ngunnawal and Ngambri people of the Canberra region and to all First Nations Australians on whose traditional lands we meet and work, and whose cultures are among the oldest continuing cultures in human history.

Aboriginal and Torres Strait Islander peoples are advised that ANU Library collections may include images, names, voices, and other representations of deceased persons.

Material in the collection may contain terms, language or views that reflect the period in which the item was created and may be considered inappropriate today.

The Role of P2Y 1 Purinergic Receptors and Cytosolic Ca2 + Hypotonically Activated Osmolyte Efflux from a Rat Hepatoma Cell Line

Date

Authors

Junankar, Pauline

Karjalainen, Ari

Kirk, Kiaran

Publisher

American Society for Biochemistry and Molecular Biology Inc

Abstract

Exposure of HTC rat hepatoma cells to a 33% decrease in extracellular osmolality caused the cytosolic Ca2+ concentration ([Ca2+]i) to increase transiently by ∼90 nM. This rise in [Ca2+]i was inhibited strongly by apyrase, grade VII (which has a low ATP/

Keywords

Keywords: Adenosinetriphosphate; Calcium; Cells; RNA; Swelling; Osmotic swelling; Biochemistry; adenosine 2' phosphate 5' phosphate; adenosine diphosphate; adenosine phosphate; adenosine triphosphatase; adenosine triphosphate; apyrase; calcium ion; chloride ion; ga

URI

http://hdl.handle.net/1885/94225

Collections

ANU Research Publications

Source

Journal of Biological Chemistry

Type

Journal article

DOI

10.1074/jbc.M204712200

Restricted until

2037-12-31

Downloads

File

Description

01_Junankar_The_Role_of_P2Y_1__Purinergic_2002.pdf (279.88 KB)