Heavy cannabis users at elevated risk of stroke: Evidence from a general population survey

dc.contributor.authorHemachandra, Dilini
dc.contributor.authorMcKetin, Rebecca
dc.contributor.authorCherbuin, Nicolas
dc.contributor.authorAnstey, Kaarin
dc.date.accessioned2016-02-24T22:41:30Z
dc.date.issued2015
dc.date.updated2016-02-24T10:12:20Z
dc.description.abstractObjective: Case reports and hospital-based case-control studies suggest that cannabis use may increase the risk of stroke. We examined the risk of non-fatal stroke or transient ischemic attack (TIA) among cannabis users in the general community. Method: A general population survey of Australians aged 20-24 years (n=2,383), 40-44 years (n=2,525) and 60-64 years (n=2,547) was used to determine the odds of lifetime stroke or TIA among participants who had smoked cannabis in the past year while adjusting for other stroke risk factors. Results: There were 153 stroke/TIA cases (2.1%). After adjusting for age cohort, past year cannabis users (n=1,043) had 3.3 times the rate of stroke/TIA (95% CI 1.8-6.3, p<0.001). The incidence rate ratio (IRR) reduced to 2.3 after adjustment for covariates related to stroke, including tobacco smoking (95% CI 1.1-4.5). Elevated stroke/TIA was specific to participants who used cannabis weekly or more often (IRR 4.7, 95% CI 2.1-10.7) with no elevation among participants who used cannabis less often. Conclusions: Heavy cannabis users in the general community have a higher rate of non-fatal stroke or transient ischemic attack than non-cannabis users.
dc.identifier.issn1326-0200
dc.identifier.urihttp://hdl.handle.net/1885/98709
dc.publisherPublic Health Association of Australia
dc.rightsAuthor/s retain copyrighten_AU
dc.sourceAustralian and New Zealand Journal of Public Health
dc.titleHeavy cannabis users at elevated risk of stroke: Evidence from a general population survey
dc.typeJournal article
dcterms.accessRightsOpen Accessen_AU
local.bibliographicCitation.lastpage5
local.bibliographicCitation.startpage1
local.contributor.affiliationHemachandra, Dilini, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMcKetin, Rebecca, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationCherbuin, Nicolas, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationAnstey, Kaarin, College of Medicine, Biology and Environment, ANU
local.contributor.authoremailu5381494@anu.edu.au
local.contributor.authoruidHemachandra, Dilini, u5381494
local.contributor.authoruidMcKetin, Rebecca, u5065925
local.contributor.authoruidCherbuin, Nicolas, u3184049
local.contributor.authoruidAnstey, Kaarin, u4038535
local.description.notesImported from ARIES
local.identifier.absfor110300 - CLINICAL SCIENCES
local.identifier.absfor111714 - Mental Health
local.identifier.absfor170100 - PSYCHOLOGY
local.identifier.ariespublicationU3488905xPUB6843
local.identifier.doi10.1111/1753-6405.12477
local.identifier.scopusID2-s2.0-84948124723
local.identifier.uidSubmittedByU3488905
local.type.statusPublished Version

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