Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy

Mills, Michelle; Yang, Nan; Weinberger, Ron; Vander Woude, Douglas; Beggs, Alan H; Easteal, Simon; North, Kathryn

Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy

Date

2001

Authors

Mills, Michelle

Yang, Nan

Weinberger, Ron

Vander Woude, Douglas

Beggs, Alan H

Easteal, Simon

North, Kathryn

Publisher

Oxford University Press

Abstract

The α-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of α-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin fil

Keywords

Keywords: actin binding protein; alpha actinin; alpha actinin 2; alpha actinin 3; dystrophin; isoprotein; unclassified drug; animal cell; animal model; article; chicken; controlled study; embryo; embryo development; evolution; gene expression; gene function; gene m

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http://hdl.handle.net/1885/93224

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ANU Research Publications

Source

Human Molecular Genetics

Type

Journal article

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2037-12-31

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Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy

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