Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy
Date
2001
Authors
Mills, Michelle
Yang, Nan
Weinberger, Ron
Vander Woude, Douglas
Beggs, Alan H
Easteal, Simon
North, Kathryn
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Volume Title
Publisher
Oxford University Press
Abstract
The α-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of α-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin fil
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Keywords: actin binding protein; alpha actinin; alpha actinin 2; alpha actinin 3; dystrophin; isoprotein; unclassified drug; animal cell; animal model; article; chicken; controlled study; embryo; embryo development; evolution; gene expression; gene function; gene m
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Source
Human Molecular Genetics
Type
Journal article
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2037-12-31
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