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Serotonin transporter polymorphisms and clinical response to sertraline across ethnicities

Date

Authors

Ng, Chee Hong

Easteal, Simon

Schweitzer, Issac

Kong Wai Ho, Brian

Aziz, Salina

Tan, Susan (Xiaoyun)

Publisher

Pergamon Press

Abstract

The aim of this pilot study was to examine the relationship between clinical response, adverse effects, sertraline (SERT) plasma concentrations and the genetic polymorphism of the serotonin transporter gene-linked polymorphic region (5HTTLPR) in 2 ethnic

Keywords

Keywords: serotonin transporter; sertraline; adult; anxiety disorder; appetite disorder; article; Caucasian; Chinese; Clinical Global Impression scale; clinical trial; controlled clinical trial; controlled study; DNA polymorphism; drug blood level; drug efficacy; d 5-HTT polymorphisms; Adverse effects; Plasma concentrations; Sertraline

URI

http://hdl.handle.net/1885/17980

Collections

ANU Research Publications

Source

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Type

Journal article

DOI

10.1016/j.pnpbp.2006.02.015

Restricted until

2037-12-31

Downloads

File

Description

01_Ng_Serotonin_transporter_2006.pdf (111.79 KB)