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Characterising nitric oxide-mediated metabolic benefits of low-dose ultraviolet radiation: a focus on brown adipose tissue

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Authors

Dhamrait, Gursimran
Panchal, Kunjal
Fleury, Naomi
Abel, Tamara N
Ancliffe, Mathew K
Crew, Rachael C
Croft, Kevin D
Fernandez, Bernadette O
Minnion, Magdalena
Hart, Prue

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Springer

Abstract

Exposure to sunlight has the potential to suppress metabolic dysfunction and obesity. We previously demonstrated that regular exposure to low-doses of ultraviolet radiation (UVR) reduced weight gain and signs of diabetes in male mice fed a high-fat diet, in part via release of nitric oxide from skin. Here, we explore further mechanistic pathways through which low-dose UVR exerts these beneficial effects.

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Source

Diabetologia

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Open Access

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Restricted until

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