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Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells

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Date

2013

Authors

Kelly, Richard D W
Rodda, AE
Dickinson, Adam
Mahmud, Arsalan
Nefzger, Christian M
Lee, William
Forsythe, John S.
Polo, Jose M
Trounce, Ian A
McKenzie, Matthew

Journal Title

Journal ISSN

Volume Title

Publisher

AlphaMed Press Inc

Abstract

Mitochondrial DNA haplotypes are associated with various phenotypes, such as altered susceptibility to disease, environmental adaptations, and aging. Accumulating evidence suggests that mitochondrial DNA is essential for cell differentiation and the cell

Description

Keywords

Keywords: mitochondrial DNA; octamer transcription factor 4; transcription factor NANOG; transcription factor Sox2; article; cell culture; cell differentiation; cell fate; copy number variation; DNA methylation; embryoid body; embryonic stem cell; energy metabolism

Citation

URI

http://hdl.handle.net/1885/72427

Collections

ANU Research Publications

Source

Stem Cells

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1002/stem.1313

Restricted until

2037-12-31

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Description
01_Kelly_Mitochondrial_DNA_haplotypes_2013.pdf (1.19 MB)

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