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A convenient synthesis of 2-(3-methyl-2,5-dioxopyrrolidin-1-yl)benzoic acid

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Date

2003

Authors

Barker, David
Brimble, Margaret A
McLeod, Malcolm

Journal Title

Journal ISSN

Volume Title

Publisher

Georg Thieme Verlag

Abstract

A new procedure for the synthesis of 2-(3-methyl-2,5-dioxopyrrolidin-1yl)benzoic acid (3) is reported via hydrogenation of 2-(3-methyl-2,5-dihydropyrrol-1-yl)benzoic acid (9) that in turn is available from fusion of anthranilic acid with citraconic anhydride. This method provides cleaner material in higher overall yield than that obtained using previously reported methods.

Description

Keywords

Keywords: Hydrides; Hydrogenation; Synthesis (chemical); Benzoic acids; Organic acids; 2 (3 methyl 2,5 dihydropyrrol 1 yl)benzoic acid; 2 (3 methyl 2,5 dioxopyrrolidin 1 yl)benzoic acid; anthranilic acid; benzoic acid derivative; citraconic anhydride; unclassified Acids; Alkaloids; Amines; Anhydrides; Hydrogenation

Citation

URI

http://hdl.handle.net/1885/53218

Collections

ANU Research Publications

Source

Synthesis

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1055/s-2003-38065

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