A convenient synthesis of 2-(3-methyl-2,5-dioxopyrrolidin-1-yl)benzoic acid
Date
Authors
Barker, David
Brimble, Margaret A
McLeod, Malcolm
Journal Title
Journal ISSN
Volume Title
Publisher
Georg Thieme Verlag
Abstract
A new procedure for the synthesis of 2-(3-methyl-2,5-dioxopyrrolidin-1yl)benzoic acid (3) is reported via hydrogenation of 2-(3-methyl-2,5-dihydropyrrol-1-yl)benzoic acid (9) that in turn is available from fusion of anthranilic acid with citraconic anhydride. This method provides cleaner material in higher overall yield than that obtained using previously reported methods.
Description
Citation
Collections
Source
Synthesis