Reversible aqueous metathesis reactions for potential application in dynamic combinatorial chemistry
Date
2010
Authors
Hunter, Luke
Condie, Glenn C
Harding, Margaret
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Publisher
Elsevier
Abstract
Solutions of heterocycles having an allyl sulfide unit and simple alkenes in 50% t-BuOH/H2O undergo reversible olefin metathesis reactions with the second generation Hoveyda-Grubbs catalyst. The choice of functional groups is limited by competitive chelation of some heterocycles with the catalyst, and other stereoelectronic effects.
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Keywords
Keywords: alkene; allyl compound; naphthalimide derivative; article; catalyst; chelation; chemical reaction; combinatorial chemistry; metathesis reaction; stereochemistry Allyl sulfides; Aqueous metathesis; Dynamic combinatorial chemistry; Reversible metathesis
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Source
Tetrahedron Letters
Type
Journal article
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Restricted until
2037-12-31
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