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A mutation in a chromosome condensin II subunit, kleisin, specifically disrupts T cell development

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Authors

Gosling, Katharine
Makaroff, Lydia
Theodoratos, Angelo
Kim, Yong Hee
Whittle, Belinda
Rui, Lixin
Wu, Hua
Hong, Nancy A
Kennedy, Gavin
Fritz, Julie-Anne

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National Academy of Sciences (USA)

Abstract

Condensins are ubiquitously expressed multiprotein complexes that are important for chromosome condensation and epigenetic regulation of gene transcription, but whose specific roles in vertebrates are poorly understood. We describe a mouse strain, nessy,

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PNAS - Proceedings of the National Academy of Sciences of the United States of America

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Restricted until

2037-12-31