Does gene dosage really matter?

Date

2007-03-22

Authors

Graves, Jennifer
Disteche, Christine M

Journal Title

Journal ISSN

Volume Title

Publisher

BioMed Central

Abstract

Mechanisms to compensate for dosage differences of genes on sex chromosomes are widespread in animals and have been thought to be critical for viability. However, in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical, and for some genes, dosage differences have even been selected for.

Description

Keywords

Keywords: cell viability; gene; gene dosage; gene expression regulation; genetic difference; human; nonhuman; priority journal; regulatory mechanism; sex chromosome; short survey; animal; bird; Drosophila; female; genetics; male; mammal; mouse; note; Animalia; Aves

Citation

Journal of Biology 6.1 (2007)

Source

Journal of Biology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1186/jbiol55

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