Total Synthesis of Sordaricin

Mander, Lewis; Thomson, Regan

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Total Synthesis of Sordaricin

Date

2003

Authors

Mander, Lewis

Thomson, Regan

Publisher

American Chemical Society

Abstract

(Matrix presented) The total synthesis of sordaricin, the diterpene aglycone of an important class of antifungal compounds, is described. Two approaches were explored, the first of which utilized a possible biogenetic intramolecular [4 + 2] cycloaddition