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αB-Crystallin inhibits the cell toxicity associated with amyloid fibril formation by κ-casein and the amyloid-β peptide

Date

Authors

Dehle, Francis C.

Ecroyd, Heath

Musgrave, Ian F.

Carver, John

Publisher

Cell Stress Society International

Abstract

Amyloid fibril formation is associated with diseases such as Alzheimer's, Parkinson's, and prion diseases. Inhibition of amyloid fibril formation by molecular chaperone proteins, such as the small heat-shock protein αB-crystallin, may play a protective r

Keywords

Keywords: alpha crystallin; amyloid beta protein; beta casein; kappa casein; Alzheimer disease; animal cell; article; binding affinity; cell viability; controlled study; cytotoxicity; enzyme inhibition; genetic association; nonhuman; Parkinson disease; prion diseas aB-Crystallin; ?-Casein; Amyloid fibril; Amyloid-ß; Cell toxicity; Small heat-shock protein

URI

http://hdl.handle.net/1885/63330

Collections

ANU Research Publications

Source

Cell Stress and Chaperones

Type

Journal article

DOI

10.1007/s12192-010-0212-z

Restricted until

2037-12-31

Downloads

File

Description

01_Dehle_αB-Crystallin_inhibits_the_2010.pdf (794.75 KB)