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Illuminating autoimmune regulators through controlled variation of the mouse genome sequence

Date

Authors

Garcia De Vinuesa, Maria Carola

Goodnow, Christopher

Publisher

Cell Press

Abstract

Gene variants in mice that have strong, Mendelian effects on autoimmune susceptibility have been one of the most productive entry points for identifying genes and processes regulating human autoimmunity. With the tools now available to map and identify ne

Keywords

Keywords: autoimmunity; disease predisposition; gene identification; gene mapping; gene sequence; genetic susceptibility; genetic variability; genome; humoral immunity; immunoregulation; lupus vulgaris; mouse; mutation; nonhuman; priority journal; review; systemic

URI

http://hdl.handle.net/1885/77851

Collections

ANU Research Publications

Source

Immunity

Type

Journal article

DOI

10.1016/j.immuni.2004.05.012

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